Monster Train 2 is a strategy game in which players control an alliance of angels and demons aboard a train to battle the Titans who have invaded Heaven. The game features five distinct clans, each offering unique gameplay mechanics and strategies across three levels of vertical defense. Players build their decks through unit recruitment, card upgrades, and a new room and equipment card system that provides strategic advantages and unit upgrades. The game’s hub, the Covenant Outpost, serves as the central location for story progression.