Genome Guardian 2, a psychedelic dive into the dark depths of the Abyss, forces gamers to constantly adapt to the vertical format of fierce firefights. Survival among aggressive microbial hordes requires constant collection of minerals and the search for life-saving augmenting polyps. The endless Versus mode has undergone a major overhaul, posing a serious challenge even for the most seasoned connoisseurs of the genre. The environment is filled with spatial anomalies and sudden mutations that radically change the rules of survival. The transformation of the standard process into a classic scrolling shooter opens up entirely new tactical horizons. Danger lurks everywhere, forcing players to react with lightning speed to the slightest changes in the macroscopic environment.

Crawl Lab is a secret laboratory built by Selen Industry deep in the mountains. Research on a new product was conducted here using a newly created artificial life form, the "Biodoll." But one day, a network-crawling AI abducts the new Biodoll and calls itself the Crawling Queen. She takes control of all objects in the laboratory. The protagonist embarks on a mission to retrieve research materials from the laboratory.