Nightmare Frontier puts players in charge of a group of miners entering a corrupted Klondike town from an alternate 1900s. The squad is sent into the settlement to fight creatures called Dread Weavers, embodiments of human phobias. Missions involve infiltrating the area, collecting resources, and returning safely to base. The events take place on an alternate American frontier, where prospects have taken on a supernatural nature. The gameplay in Nightmare Frontier is built around combinations of well-aimed shots to suppress opponents before closing in. Soldiers are able to push, parry, and combine attacks, changing the balance of power on the battlefield.