ANNO Mutationem v1.2.00.00 (upd.28.01.2026) + all DLC - RUNE

ANNO Mutationem - full game download
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Game updated on 28-01-2026, 14:36. Current version: v1.2.00.00 (upd.28.01.2026) + all DLC.
4.8/ 5
Community Rating: 189 votes

About The Game

ANNO Mutationem — is a unique adventure that takes you into a cyberpunk and dark future. This time you have to use all your skills and knowledge to achieve a favorable result and complete your main task. You have to play for a girl who works as a mercenary. Her next task is connected with a huge metropolis, in which mega-corporations began to actively develop, which seized power, created terrible experiments and simply did not value human lives. The task is that she needs to destroy the enemies and try to use any of her abilities to win. But who would have thought that these particular corporations are associated with its not so bright and very gloomy past.

You can freely travel around the metropolis, exploring the expanses. In this case, you will have the opportunity to fight with different creatures and try by any means to achieve success. You have to fight with other mercenaries and even with dangerous creatures that will amaze you with their cruelty and size. In any case, you will have the opportunity to simply understand this story and draw certain conclusions. The main thing is to stay alive and uncover the secrets of your past.

NOTE. Uploaded version: 28 January 2026 [v1.2.00.00]. This is Full Release and latest version of game. The game is already Packaged in ISO File and ready to run the game, read the instruction below.

This release is standalone and includes the following DLC:

  • ANNO: Mutationem Original Game Soundtrack Complete Edition
  • ANNO: Mutationem Collectors Upgrade Pack

Game Details

System Requirements

MINIMUM:

Requires a 64-bit processor and operating system
OS: Windows 7 (64 bit) or Newer
Processor: Intel i3+
Memory: 4 GB RAM
Graphics: GeForce GT 1030
DirectX: Version 11

RECOMMENDED:
Requires a 64-bit processor and operating system
OS: Windows 10
Processor: Intel i5+
Memory: 8 GB RAM
Graphics: GeForce GTX 1050
DirectX: Version 11

Screenshots

ANNO Mutationem gameplay screenshot 1
ANNO Mutationem gameplay screenshot 2
ANNO Mutationem gameplay screenshot 3

Video

How to Install

1. The first thing we do is download the game’s installation files. 
2. Mount or burn the ISO image in the disk emulator (UltraISO program). 
3. During the installation, we specify the location on the disk where we want to install it. 
4. Wait until the installation process is complete, a shortcut will appear on the desktop. 
5. Copy the contents of the folder «RUNE» in the folder with the game. 
6. Start the game.


Download update only: ANNO Mutationem Update v20221114-ANOMALY [ 860.0 MB ]

  1. Unpack release.
  2. Install the Update to where you installed the game.
  3. Copy contents from «ANOMALY» dir into Game root.
  4. Enjoy!

Download update only: ANNO.Mutationem.Update.v1.05.07-ANOMALY [ 892 MB ]
Download update only: 
ANNO.Mutationem.Update.v1.04.03-ANOMALY | MIRROR [ 1.93 GB ]

Download ANNO Mutationem v1.2.00.00 (upd.28.01.2026) + all DLC — RUNE

File Size: 11.81 GB
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Other Versions & DLCs

Game Update History

  • ANNO Mutationem v1.05.07.02 → v1.2.00.00 [ 28.01.2026 ]
  • ANNO Mutationem v20221114 → v1.05.07.02 [ 14.04.2023 ]
  • ANNO Mutationem v1.05.07 → Update v20221114 [ 11.10.2022 ]
  • ANNO Mutationem v1.04.03 → Update v1.05.07 [ 11.10.2022 ]
  • ANNO Mutationem v1.0 → Update v1.04.03 [ 04.06.2022 ]
  • ANNO Mutationem demo → v1.0 [ 17.03.2022 ]
  • ANNO Mutationem → demo [ 18.02.2022 ]

Comments 2

  1. Game is updated to v1.05.07.02 (upd.14.04.2023)
    ------
    Guardian of the Online Empire
  2. Skigameco 28 January 2026 14:34
    Today we're launching a new update! We call it Boss Rogue! It's basically a Boss Rush mode but with some rogue-like elements put in there, available for players who have completed the game! See if can still headbutt mutant lizards and handsome long haired nemesis'es (nemessii?) when both lady luck and your strategic battle brain play a big role in how you go into battle. Oh and let us know your PR's once you did plz!
     
    Also, we've released the Steam Trading Cards for Anno, check 'em out! Please see below for the in-depth change log for this update, and if you run into any issues or bugs, please let us know either via steam, discord or email!
     
    New Content
    -New Mode: BOSS Rogue – Unlocked automatically after completing the main story. A brand-new rogue-lite inspired Boss Challenge mode using all the game's bosses' is now live!
     
    New Platform:
    -Mac Version – Officially released and available now.
     
    -High Difficulty Mode
    You can now select "Highest Difficulty" right from the start.
     
    -Steam Trading Cards
    –Now officially available for collection and trading.
     
    Optimizations & Improvements
    -Reduced input delay for gamepad controls.
    -Improved scene loading performance in some areas.
    -Upgraded engine backend for better performance.
    -Optimized minigames.
    ------
    Guardian of the Online Empire
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